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Comprehensive Genomic Profiling of Hodgkin Lymphoma Reveals Recurrently Mutated Genes and Increased Mutation Burden

BACKGROUND. The genomic landscape of Hodgkin lymphoma (HL) has been difficult to characterize due to the paucity of neoplastic cells and an abundant microenvironment. Such characterization is needed in order to improve treatment strategies. MATERIALS AND METHODS. We performed comprehensive genomic p...

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Detalles Bibliográficos
Autores principales: Liang, Winnie S., Vergilio, Jo‐Anne, Salhia, Bodour, Huang, Helen J., Oki, Yasuhiro, Garrido‐Laguna, Ignacio, Park, Haeseong, Westin, Jason R., Meric‐Bernstam, Funda, Fabrizio, David, Miller, Vincent A., Stephens, Philip J., Fanale, Michelle A., Ross, Jeffrey S., Janku, Filip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369943/
https://www.ncbi.nlm.nih.gov/pubmed/30108156
http://dx.doi.org/10.1634/theoncologist.2018-0058