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Multiple infection of cells changes the dynamics of basic viral evolutionary processes

The infection of cells by multiple copies of a given virus can impact viral evolution in a variety of ways, yet some of the most basic evolutionary dynamics remain underexplored. Using computational models, we investigate how infection multiplicity affects the fixation probability of mutants, the ra...

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Detalles Bibliográficos
Autores principales: Wodarz, Dominik, Levy, David N., Komarova, Natalia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369963/
https://www.ncbi.nlm.nih.gov/pubmed/30788146
http://dx.doi.org/10.1002/evl3.95