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Synthesis of C(3)-symmetric star-shaped molecules containing α-amino acids and dipeptides via Negishi coupling as a key step
We demonstrate a new synthetic strategy toward star-shaped C(3)-symmetric molecules containing α-amino acid (AAA) derivatives and dipeptides. In this regard, trimerization and Negishi cross-coupling reactions are used as the key steps starting from readily available 4’-iodoacetophenone and L-serine....
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369998/ https://www.ncbi.nlm.nih.gov/pubmed/30800186 http://dx.doi.org/10.3762/bjoc.15.33 |