Targeting EZH2 in Multiple Myeloma—Multifaceted Anti-Tumor Activity

The enhancer of zeste homolog 2 (EZH2) is the enzymatic subunit of the polycomb repressive complex 2 (PRC2) that exerts important functions during normal development as well as disease. PRC2 through EZH2 tri-methylates histone H3 lysine tail residue 27 (H3K27me3), a modification associated with repr...

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Detalles Bibliográficos
Autores principales: Alzrigat, Mohammad, Jernberg-Wiklund, Helena, Licht, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370027/
https://www.ncbi.nlm.nih.gov/pubmed/30761216
http://dx.doi.org/10.3390/epigenomes2030016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370027/
https://www.ncbi.nlm.nih.gov/pubmed/30761216
http://dx.doi.org/10.3390/epigenomes2030016

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