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Correlation of CYP2C19 genotype with plasma voriconazole exposure in South-western Chinese Han patients with invasive fungal infections

The aim of this study was to investigate the correlation between CYP2C19 genotype and dose-adjusted voriconazole (VCZ) trough concentrations (C(0)/dose). We analyzed the correlation between CYP2C19(∗)2(681G>A), CYP2C19(∗)3(636G>A), and CYP2C19(∗)17(-806C>T) genetic polymorphisms and the dos...

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Detalles Bibliográficos
Autores principales: Miao, Qiang, Tang, Jiang-Tao, van Gelder, Teun, Li, Ya-Mei, Bai, Yang-Juan, Zou, Yuan-Gao, Wang, Lan-Lan, Shi, Yun-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370172/
https://www.ncbi.nlm.nih.gov/pubmed/30653146
http://dx.doi.org/10.1097/MD.0000000000014137