Cargando…

Mutation in DDM1 inhibits the homology directed repair of double strand breaks

In all organisms, DNA damage must be repaired quickly and properly, as it can be lethal for cells. Because eukaryotic DNA is packaged into nucleosomes, the structural units of chromatin, chromatin modification is necessary during DNA damage repair and is achieved by histone modification and chromati...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Seung Hee, Ryu, Tae Ho, Kim, Jeong-Il, Lee, Sungbeom, Lee, Seung Sik, Kim, Jin-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370192/
https://www.ncbi.nlm.nih.gov/pubmed/30742642
http://dx.doi.org/10.1371/journal.pone.0211878