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Prediction of ultra-high-order antibiotic combinations based on pairwise interactions
Drug combinations are a promising approach to achieve high efficacy at low doses and to overcome resistance. Drug combinations are especially useful when drugs cannot achieve effectiveness at tolerable doses, as occurs in cancer and tuberculosis (TB). However, discovery of effective drug combination...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370231/ https://www.ncbi.nlm.nih.gov/pubmed/30699106 http://dx.doi.org/10.1371/journal.pcbi.1006774 |