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Prediction of ultra-high-order antibiotic combinations based on pairwise interactions

Drug combinations are a promising approach to achieve high efficacy at low doses and to overcome resistance. Drug combinations are especially useful when drugs cannot achieve effectiveness at tolerable doses, as occurs in cancer and tuberculosis (TB). However, discovery of effective drug combination...

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Detalles Bibliográficos
Autores principales: Katzir, Itay, Cokol, Murat, Aldridge, Bree B., Alon, Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370231/
https://www.ncbi.nlm.nih.gov/pubmed/30699106
http://dx.doi.org/10.1371/journal.pcbi.1006774