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Network hubs affect evolvability

The regulatory processes in cells are typically organized into complex genetic networks. However, it is still unclear how this network structure modulates the evolution of cellular regulation. One would expect that mutations in central and highly connected modules of a network (so-called hubs) would...

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Detalles Bibliográficos
Autores principales: Helsen, Jana, Frickel, Jens, Jelier, Rob, Verstrepen, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370235/
https://www.ncbi.nlm.nih.gov/pubmed/30699103
http://dx.doi.org/10.1371/journal.pbio.3000111