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Lysine 27 of replication-independent histone H3.3 is required for Polycomb target gene silencing but not for gene activation
Proper determination of cell fates depends on epigenetic information that is used to preserve memory of decisions made earlier in development. Post-translational modification of histone residues is thought to be a central means by which epigenetic information is propagated. In particular, modificati...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370247/ https://www.ncbi.nlm.nih.gov/pubmed/30699116 http://dx.doi.org/10.1371/journal.pgen.1007932 |