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Lysine 27 of replication-independent histone H3.3 is required for Polycomb target gene silencing but not for gene activation

Proper determination of cell fates depends on epigenetic information that is used to preserve memory of decisions made earlier in development. Post-translational modification of histone residues is thought to be a central means by which epigenetic information is propagated. In particular, modificati...

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Detalles Bibliográficos
Autores principales: Leatham-Jensen, Mary, Uyehara, Christopher M., Strahl, Brian D., Matera, A. Gregory, Duronio, Robert J., McKay, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370247/
https://www.ncbi.nlm.nih.gov/pubmed/30699116
http://dx.doi.org/10.1371/journal.pgen.1007932