Oncogenic KSHV-encoded interferon regulatory factor upregulates HMGB2 and CMPK1 expression to promote cell invasion by disrupting a complex lncRNA-OIP5-AS1/miR-218-5p network

Kaposi’s sarcoma (KS), a highly disseminated tumor of hyperproliferative spindle endothelial cells, is the most common AIDS-associated malignancy caused by infection of Kaposi’s sarcoma-associated herpesvirus (KSHV). KSHV-encoded viral interferon regulatory factor 1 (vIRF1) is a viral oncogene but i...

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Detalles Bibliográficos
Autores principales: Li, Wan, Wang, Qingxia, Feng, Qi, Wang, Fei, Yan, Qin, Gao, Shou-Jiang, Lu, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370251/
https://www.ncbi.nlm.nih.gov/pubmed/30699189
http://dx.doi.org/10.1371/journal.ppat.1007578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370251/
https://www.ncbi.nlm.nih.gov/pubmed/30699189
http://dx.doi.org/10.1371/journal.ppat.1007578

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