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Oncogenic KSHV-encoded interferon regulatory factor upregulates HMGB2 and CMPK1 expression to promote cell invasion by disrupting a complex lncRNA-OIP5-AS1/miR-218-5p network
Kaposi’s sarcoma (KS), a highly disseminated tumor of hyperproliferative spindle endothelial cells, is the most common AIDS-associated malignancy caused by infection of Kaposi’s sarcoma-associated herpesvirus (KSHV). KSHV-encoded viral interferon regulatory factor 1 (vIRF1) is a viral oncogene but i...
Autores principales: | Li, Wan, Wang, Qingxia, Feng, Qi, Wang, Fei, Yan, Qin, Gao, Shou-Jiang, Lu, Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370251/ https://www.ncbi.nlm.nih.gov/pubmed/30699189 http://dx.doi.org/10.1371/journal.ppat.1007578 |
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