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Impact of the SPOP Mutant Subtype on the Interpretation of Clinical Parameters in Prostate Cancer

PURPOSE: Molecular characterization of prostate cancer, including The Cancer Genome Atlas, has revealed distinct subtypes with underlying genomic alterations. One of these core subtypes, SPOP (speckle-type POZ protein) mutant prostate cancer, has previously only been identifiable via DNA sequencing,...

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Detalles Bibliográficos
Autores principales: Liu, Deli, Takhar, Mandeep, Alshalalfa, Mohammed, Erho, Nicholas, Shoag, Jonathan, Jenkins, Robert B., Karnes, R. Jeffrey, Ross, Ashley E., Schaeffer, Edward M., Rubin, Mark A., Trock, Bruce, Klein, Eric A., Den, Robert B., Tomlins, Scott A., Spratt, Daniel E., Davicioni, Elai, Sboner, Andrea, Barbieri, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370327/
https://www.ncbi.nlm.nih.gov/pubmed/30761387
http://dx.doi.org/10.1200/PO.18.00036