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The Downregulation of MicroRNA hsa-miR-340-5p in IAV-Infected A549 Cells Suppresses Viral Replication by Targeting RIG-I and OAS2

The influenza A virus poses serious public health challenges worldwide. Strikingly, small noncoding microRNAs (miRNAs) that modulate gene expression are closely involved in antiviral responses, although the underlying mechanisms are essentially unknown. We now report that microRNA-340 (miR340) is do...

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Detalles Bibliográficos
Autores principales: Zhao, Lianzhong, Zhang, Xiaohan, Wu, Zhu, Huang, Kun, Sun, Xiaomei, Chen, Huanchun, Jin, Meilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370596/
https://www.ncbi.nlm.nih.gov/pubmed/30753994
http://dx.doi.org/10.1016/j.omtn.2018.12.014