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Oral Metallo-Beta-Lactamase Protects the Gut Microbiome From Carbapenem-Mediated Damage and Reduces Propagation of Antibiotic Resistance in Pigs

Antibiotics can damage the gut microbiome, leading to serious adventitious infections and emergence of antibiotic resistant pathogens. Antibiotic inactivation in the GI tract represents a strategy to protect colonic microbiota integrity and reduce antibiotic resistance. Clinical utility of this appr...

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Detalles Bibliográficos
Autores principales: Connelly, Sheila, Fanelli, Brian, Hasan, Nur A., Colwell, Rita R., Kaleko, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370672/
https://www.ncbi.nlm.nih.gov/pubmed/30804903
http://dx.doi.org/10.3389/fmicb.2019.00101