HIF-1α-Deficiency in Myeloid Cells Leads to a Disturbed Accumulation of Myeloid Derived Suppressor Cells (MDSC) During Pregnancy and to an Increased Abortion Rate in Mice

Abortions are the most important reason for unintentional childlessness. During pregnancy, maternal immune cells are in close contact to cells of the semi-allogeneic fetus. Dysregulation of the maternal immune system leading to defective adaptation to pregnancy often plays a role in pathogenesis of...

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Detalles Bibliográficos
Autores principales: Köstlin-Gille, Natascha, Dietz, Stefanie, Schwarz, Julian, Spring, Bärbel, Pauluschke-Fröhlich, Jan, Poets, Christian F., Gille, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370686/
https://www.ncbi.nlm.nih.gov/pubmed/30804946
http://dx.doi.org/10.3389/fimmu.2019.00161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370686/
https://www.ncbi.nlm.nih.gov/pubmed/30804946
http://dx.doi.org/10.3389/fimmu.2019.00161

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