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Synthesis of [(18)F]Favipiravir and Biodistribution in C3H/HeN Mice as Assessed by Positron Emission Tomography

Favipiravir (T705; 6-fluoro-3-hydroxypyrazine-2-carboxamide) is a pyrazine analog that has demonstrated potent antiviral activity against a broad spectrum of viruses in multiple in vivo disease models. To better understand the compounds anti-viral activity, assessment of the drug’s biodistribution a...

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Detalles Bibliográficos
Autores principales: Bocan, Thomas M., Basuli, Falguni, Stafford, Robert G., Brown, Jennifer L., Zhang, Xiang, Duplantier, Allen J., Swenson, Rolf E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370782/
https://www.ncbi.nlm.nih.gov/pubmed/30741966
http://dx.doi.org/10.1038/s41598-018-37866-z