Cargando…

Glucocorticoid receptor in astrocytes regulates midbrain dopamine neurodegeneration through connexin hemichannel activity

The precise contribution of astrocytes in neuroinflammatory process occurring in Parkinson’s disease (PD) is not well characterized. In this study, using GR(Cx30CreERT2) mice that are conditionally inactivated for glucocorticoid receptor (GR) in astrocytes, we have examined the actions of astrocytic...

Descripción completa

Detalles Bibliográficos
Autores principales: Maatouk, Layal, Yi, Chenju, Carrillo-de Sauvage, Maria-Angeles, Compagnion, Anne-Claire, Hunot, Stéphane, Ezan, Pascal, Hirsch, Etienne C., Koulakoff, Annette, Pfrieger, Frank W, Tronche, François, Leybaert, Luc, Giaume, Christian, Vyas, Sheela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370798/
https://www.ncbi.nlm.nih.gov/pubmed/30006609
http://dx.doi.org/10.1038/s41418-018-0150-3