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Glucocorticoid receptor in astrocytes regulates midbrain dopamine neurodegeneration through connexin hemichannel activity
The precise contribution of astrocytes in neuroinflammatory process occurring in Parkinson’s disease (PD) is not well characterized. In this study, using GR(Cx30CreERT2) mice that are conditionally inactivated for glucocorticoid receptor (GR) in astrocytes, we have examined the actions of astrocytic...
Autores principales: | Maatouk, Layal, Yi, Chenju, Carrillo-de Sauvage, Maria-Angeles, Compagnion, Anne-Claire, Hunot, Stéphane, Ezan, Pascal, Hirsch, Etienne C., Koulakoff, Annette, Pfrieger, Frank W, Tronche, François, Leybaert, Luc, Giaume, Christian, Vyas, Sheela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370798/ https://www.ncbi.nlm.nih.gov/pubmed/30006609 http://dx.doi.org/10.1038/s41418-018-0150-3 |
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