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Downregulation of PRMT1 promotes the senescence and migration of a non-MYCN amplified neuroblastoma SK-N-SH cells

Protein arginine methyltransferase 1 (PRMT1) catalyzing the formation of asymmetric dimethylarginines has been implicated in cancer development, metastasis, and prognosis. In this study, we investigated the effects of low PRMT1 levels on a non-MYCN amplified neuroblastoma SK-N-SH cell line. Stable P...

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Detalles Bibliográficos
Autores principales: Lee, Yu-Jen, Chang, Wen-Wei, Chang, Chien-Ping, Liu, Tsung-Yun, Chuang, Chun-Yi, Qian, Kun, Zheng, Y. George, Li, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370813/
https://www.ncbi.nlm.nih.gov/pubmed/30741995
http://dx.doi.org/10.1038/s41598-018-38394-6