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Redundant and receptor-specific activities of TRADD, RIPK1 and FADD in death receptor signaling

We evaluated redundant and receptor-specific activities of TRADD, RIPK1, and FADD in RIPK3-expressing HeLa cells lacking expression of these proteins or any combination of two of these factors. We confirmed the opposing role of FADD in TNF- and TRAIL-induced necroptosis and observed an anti-necropto...

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Detalles Bibliográficos
Autores principales: Füllsack, Simone, Rosenthal, Alevtina, Wajant, Harald, Siegmund, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370826/
https://www.ncbi.nlm.nih.gov/pubmed/30741924
http://dx.doi.org/10.1038/s41419-019-1396-5