Japanese encephalitis virus neuropenetrance is driven by mast cell chymase

Japanese encephalitis virus (JEV) is a leading cause of viral encephalitis. However, the mechanisms of JEV penetration of the blood-brain-barrier (BBB) remain poorly understood. Mast cells (MCs) are granulated innate immune sentinels located perivascularly, including at the BBB. Here we show that JE...

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Detalles Bibliográficos
Autores principales: Hsieh, Justin T., Rathore, Abhay P. S., Soundarajan, Gayathri, St. John, Ashley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370868/
https://www.ncbi.nlm.nih.gov/pubmed/30742008
http://dx.doi.org/10.1038/s41467-019-08641-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370868/
https://www.ncbi.nlm.nih.gov/pubmed/30742008
http://dx.doi.org/10.1038/s41467-019-08641-z

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