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Japanese encephalitis virus neuropenetrance is driven by mast cell chymase
Japanese encephalitis virus (JEV) is a leading cause of viral encephalitis. However, the mechanisms of JEV penetration of the blood-brain-barrier (BBB) remain poorly understood. Mast cells (MCs) are granulated innate immune sentinels located perivascularly, including at the BBB. Here we show that JE...
Autores principales: | Hsieh, Justin T., Rathore, Abhay P. S., Soundarajan, Gayathri, St. John, Ashley L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370868/ https://www.ncbi.nlm.nih.gov/pubmed/30742008 http://dx.doi.org/10.1038/s41467-019-08641-z |
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