A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation

Most metazoan embryos commence development with rapid, transcriptionally silent cell divisions, with genome activation delayed until the mid-blastula transition (MBT). However, a set of genes escapes global repression and gets activated before MBT. Here we describe the formation and the spatio-tempo...

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Detalles Bibliográficos
Autores principales: Hadzhiev, Yavor, Qureshi, Haseeb K., Wheatley, Lucy, Cooper, Ledean, Jasiulewicz, Aleksandra, Van Nguyen, Huy, Wragg, Joseph W., Poovathumkadavil, Divyasree, Conic, Sascha, Bajan, Sarah, Sik, Attila, Hutvàgner, György, Tora, Làszlò, Gambus, Agnieszka, Fossey, John S., Müller, Ferenc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370886/
https://www.ncbi.nlm.nih.gov/pubmed/30741925
http://dx.doi.org/10.1038/s41467-019-08487-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370886/
https://www.ncbi.nlm.nih.gov/pubmed/30741925
http://dx.doi.org/10.1038/s41467-019-08487-5

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