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Claudin-7 gene knockout causes destruction of intestinal structure and animal death in mice

BACKGROUND: Claudin-7, one of the important components of cellular tight junctions, is currently considered to be expressed abnormally in colorectal inflammation and colorectal cancer. However, there is currently no effective animal model to study its specific mechanism. Therefore, we constructed th...

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Detalles Bibliográficos
Autores principales: Xu, Chang, Wang, Kun, Ding, Yu-Han, Li, Wen-Jing, Ding, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371004/
https://www.ncbi.nlm.nih.gov/pubmed/30774273
http://dx.doi.org/10.3748/wjg.v25.i5.584