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Beta 3 Adrenergic Receptor Activation Rescues Metabolic Dysfunction in Female Estrogen Receptor Alpha-Null Mice

Metabolic disease risk escalates following menopause. The mechanism is not fully known, but likely involves reduced signaling through estrogen receptor alpha (ERα), which is highly expressed in brown and white adipose tissue (BAT and WAT). Objective: Test the hypothesis that uncoupling protein (UCP1...

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Detalles Bibliográficos
Autores principales: Clookey, Stephanie L., Welly, Rebecca J., Shay, Dusti, Woodford, Makenzie L., Fritsche, Kevin L., Rector, R. Scott, Padilla, Jaume, Lubahn, Dennis B., Vieira-Potter, Victoria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371032/
https://www.ncbi.nlm.nih.gov/pubmed/30804793
http://dx.doi.org/10.3389/fphys.2019.00009