Cargando…

Novel and Potent Dopamine D(2) Receptor Go-Protein Biased Agonists

[Image: see text] The discovery of functionally biased and physiologically beneficial ligands directed toward G-protein coupled receptors (GPCRs) has provided the impetus to design dopamine D(2) receptor (D(2)R) targeted molecules that may be therapeutically advantageous for the treatment of certain...

Descripción completa

Detalles Bibliográficos
Autores principales: Bonifazi, Alessandro, Yano, Hideaki, Guerrero, Adrian M., Kumar, Vivek, Hoffman, Alexander F., Lupica, Carl R., Shi, Lei, Newman, Amy Hauck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371206/
https://www.ncbi.nlm.nih.gov/pubmed/30775693
http://dx.doi.org/10.1021/acsptsci.8b00060