Blockade of glycolysis-dependent contraction by oroxylin a via inhibition of lactate dehydrogenase-a in hepatic stellate cells

BACKGROUND: Contraction of hepatic stellate cells (HSCs) plays an important role in the pathogenesis of liver fibrosis by regulating sinusoidal blood flow and extracellular matrix remodeling. Here, we investigated how HSC contraction was affected by the natural compound oroxylin A, and elucidated th...

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Detalles Bibliográficos
Autores principales: Wang, Feixia, Jia, Yan, Li, Mengmeng, Wang, Ling, Shao, Jiangjuan, Guo, Qinglong, Tan, Shanzhong, Ding, Hai, Chen, Anping, Zhang, Feng, Zheng, Shizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371416/
https://www.ncbi.nlm.nih.gov/pubmed/30744642
http://dx.doi.org/10.1186/s12964-019-0324-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371416/
https://www.ncbi.nlm.nih.gov/pubmed/30744642
http://dx.doi.org/10.1186/s12964-019-0324-8

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