Cargando…

DA-JC1 improves learning and memory by antagonizing Aβ31–35-induced circadian rhythm disorder

Studies have shown that a normal circadian rhythm is crucial to learning and memory. Circadian rhythm disturbances that occur at early stages of Alzheimer’s disease (AD) aggravate the progression of the disease and further reduce learning and memory in AD patients. The novel, dual GLP-1R/GIPR agonis...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Li, Zhang, Rui, Hou, Xiaohong, Wang, Changtu, Guo, Shuai, Ning, Na, Sun, Cong, Yuan, Yuan, Li, Lin, Hölscher, Christian, Wang, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371467/
https://www.ncbi.nlm.nih.gov/pubmed/30744651
http://dx.doi.org/10.1186/s13041-019-0432-9