Haploinsufficiency of autism causative gene Tbr1 impairs olfactory discrimination and neuronal activation of the olfactory system in mice

BACKGROUND: Autism spectrum disorders (ASD) exhibit two clusters of core symptoms, i.e., social and communication impairment, and repetitive behaviors and sensory abnormalities. Our previous study demonstrated that TBR1, a causative gene of ASD, controls axonal projection and neuronal activation of...

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Detalles Bibliográficos
Autores principales: Huang, Tzyy-Nan, Yen, Tzu-Li, Qiu, Lily R., Chuang, Hsiu-Chun, Lerch, Jason P., Hsueh, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371489/
https://www.ncbi.nlm.nih.gov/pubmed/30792833
http://dx.doi.org/10.1186/s13229-019-0257-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371489/
https://www.ncbi.nlm.nih.gov/pubmed/30792833
http://dx.doi.org/10.1186/s13229-019-0257-5

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