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Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS

Frontotemporal lobar degeneration (FTLD) is pathologically subdivided based on the presence of particular pathological proteins that are identified in inclusion bodies observed post-mortem. The FTLD-FUS subgroup is defined by the presence of the fused in sarcoma protein (FUS) in pathological inclusi...

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Detalles Bibliográficos
Autores principales: Gittings, Lauren M., Foti, Sandrine C., Benson, Bridget C., Gami-Patel, Priya, Isaacs, Adrian M., Lashley, Tammaryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371513/
https://www.ncbi.nlm.nih.gov/pubmed/30755280
http://dx.doi.org/10.1186/s40478-019-0673-y