Cargando…

Phenylboronic acid-modified hollow silica nanoparticles for dual-responsive delivery of doxorubicin for targeted tumor therapy

This work reports a multifunctional nanocarrier based on hollow mesoporous silica nanoparticles (HMSNs) for targeting tumor therapy. Doxorubicin (DOX) was loaded into HMSNs and blocked with cytochrome C conjugated lactobionic acid (CytC–LA) via redox-cleavable disulfide bonds and pH-disassociation b...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Ling, Zhang, Qingfeng, Dai, Liangliang, Shen, Xinkun, Chen, Weizhen, Cai, Kaiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371689/
https://www.ncbi.nlm.nih.gov/pubmed/30792886
http://dx.doi.org/10.1093/rb/rbw045