Refractory and metastatic infantile fibrosarcoma harboring LMNA–NTRK1 fusion shows complete and durable response to crizotinib

Infantile fibrosarcoma (IFS) is a rare soft-tissue sarcoma, which classically presents as an aggressive and rapidly enlarging tumor over the distal extremities of children in their first year of life. The presence of ETV6 and NTRK3 gene rearrangement is characteristic of IFS, which can be detected o...

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Detalles Bibliográficos
Autores principales: Bender, Jonathan, Anderson, Bailey, Bloom, David A., Rabah, Raja, McDougall, Rhonda, Vats, Pankaj, Mody, Rajen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371745/
https://www.ncbi.nlm.nih.gov/pubmed/30709876
http://dx.doi.org/10.1101/mcs.a003376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371745/
https://www.ncbi.nlm.nih.gov/pubmed/30709876
http://dx.doi.org/10.1101/mcs.a003376

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