Hematologic malignancies and Li–Fraumeni syndrome

Li–Fraumeni syndrome (LFS) is an autosomal dominant condition associated with a high risk of a broad range of childhood- and adult-onset cancers. LFS is related to germline mutations of the tumor-suppressor gene TP53. The most common reported leukemia associated with LFS is hypodiploid acute lymphob...

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Detalles Bibliográficos
Autores principales: Swaminathan, Mahesh, Bannon, Sarah A., Routbort, Mark, Naqvi, Kiran, Kadia, Tapan M., Takahashi, Koichi, Alvarado, Yesid, Ravandi-Kashani, Farhad, Patel, Keyur P., Champlin, Richard, Kantarjian, Hagop, Strong, Louise, DiNardo, Courtney D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371746/
https://www.ncbi.nlm.nih.gov/pubmed/30709875
http://dx.doi.org/10.1101/mcs.a003210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371746/
https://www.ncbi.nlm.nih.gov/pubmed/30709875
http://dx.doi.org/10.1101/mcs.a003210

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