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Evolutionary effects of the AID/APOBEC family of mutagenic enzymes on human gamma-herpesviruses

The human gamma-herpesviruses, Epstein–Barr virus and Kaposi's sarcoma-associated herpesvirus, establish lifelong latency in B cells and are associated with multiple malignancies. Virus-host coevolution often drive changes in both host immunity and in the viral genome. We consider one host immu...

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Detalles Bibliográficos
Autores principales: Martinez, Teresa, Shapiro, Maxwell, Bhaduri-McIntosh, Sumita, MacCarthy, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371749/
https://www.ncbi.nlm.nih.gov/pubmed/30792902
http://dx.doi.org/10.1093/ve/vey040