T cell receptor cross-reactivity expanded by dramatic peptide/MHC adaptability

T cell receptor cross-reactivity allows a fixed T cell repertoire to respond to a much larger universe of potential antigens. Recent work has emphasized the importance of peptide structural and chemical homology, as opposed to sequence similarity, in T cell receptor cross-reactivity. Surprisingly th...

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Detalles Bibliográficos
Autores principales: Riley, Timothy P., Hellman, Lance M., Gee, Marvin H., Mendoza, Juan L., Alonso, Jesus A., Foley, Kendra C., Nishimura, Michael. I., Vander Kooi, Craig W., Garcia, K. Christopher, Baker, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371774/
https://www.ncbi.nlm.nih.gov/pubmed/30224695
http://dx.doi.org/10.1038/s41589-018-0130-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371774/
https://www.ncbi.nlm.nih.gov/pubmed/30224695
http://dx.doi.org/10.1038/s41589-018-0130-4

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