Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity

The epithelial-specific splicing regulators Esrp1 and Esrp2 are required for mammalian development, including establishment of epidermal barrier functions. However, the mechanisms by which Esrp ablation causes defects in epithelial barriers remain undefined. We determined that the ablation of Esrp1...

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Detalles Bibliográficos
Autores principales: Lee, SungKyoung, Cieply, Benjamin, Yang, Yueqin, Peart, Natoya, Glaser, Carl, Chan, Patricia, Carstens, Russ P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371790/
https://www.ncbi.nlm.nih.gov/pubmed/30485810
http://dx.doi.org/10.1016/j.celrep.2018.10.097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371790/
https://www.ncbi.nlm.nih.gov/pubmed/30485810
http://dx.doi.org/10.1016/j.celrep.2018.10.097

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