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Anti-inflammatory drug-eluting implant model system to prevent wear particle-induced periprosthetic osteolysis

BACKGROUND: Aseptic loosening, as a consequence of an extended inflammatory reaction induced by wear particles, has been classified as one of the most common complications of total joint replacement (TJR). Despite its high incidence, no therapeutical approach has yet been found to prevent aseptic lo...

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Detalles Bibliográficos
Autores principales: Rivera, Melissa C, Perni, Stefano, Sloan, Alastair, Prokopovich, Polina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371946/
https://www.ncbi.nlm.nih.gov/pubmed/30804671
http://dx.doi.org/10.2147/IJN.S188193