Identification of a small molecule inhibitor of Ebola virus genome replication and transcription using in silico screening

Ebola virus (EBOV) causes a severe haemorrhagic fever in humans and has a mortality rate over 50%. With no licensed drug treatments available, EBOV poses a significant threat. Investigations into possible therapeutics have been severely hampered by the classification of EBOV as a BSL4 pathogen. Here...

Descripción completa

Detalles Bibliográficos
Autores principales: Easton, Victoria, McPhillie, Martin, Garcia-Dorival, Isabel, Barr, John N., Edwards, Thomas A., Foster, Richard, Fishwick, Colin, Harris, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371959/
https://www.ncbi.nlm.nih.gov/pubmed/29870771
http://dx.doi.org/10.1016/j.antiviral.2018.06.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371959/
https://www.ncbi.nlm.nih.gov/pubmed/29870771
http://dx.doi.org/10.1016/j.antiviral.2018.06.003

Ejemplares similares