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Identification of a small molecule inhibitor of Ebola virus genome replication and transcription using in silico screening

Ebola virus (EBOV) causes a severe haemorrhagic fever in humans and has a mortality rate over 50%. With no licensed drug treatments available, EBOV poses a significant threat. Investigations into possible therapeutics have been severely hampered by the classification of EBOV as a BSL4 pathogen. Here...

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Detalles Bibliográficos
Autores principales:	Easton, Victoria, McPhillie, Martin, Garcia-Dorival, Isabel, Barr, John N., Edwards, Thomas A., Foster, Richard, Fishwick, Colin, Harris, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371959/ https://www.ncbi.nlm.nih.gov/pubmed/29870771 http://dx.doi.org/10.1016/j.antiviral.2018.06.003

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