Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells

Induction of protective vaccine responses, governed by the successful generation of antigen-specific anti-bodies and long-lived memory T cells, is increasingly impaired with age. Regulation of the T cell proteome by a dynamic network of microRNAs is crucial to T cell responses. Here, we show that ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Chulwoo, Hu, Bin, Jadhav, Rohit R., Jin, Jun, Zhang, Huimin, Cavanagh, Mary M., Akondy, Rama S., Ahmed, Rafi, Weyand, Cornelia M., Goronzy, Jörg J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371971/
https://www.ncbi.nlm.nih.gov/pubmed/30463012
http://dx.doi.org/10.1016/j.celrep.2018.10.074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371971/
https://www.ncbi.nlm.nih.gov/pubmed/30463012
http://dx.doi.org/10.1016/j.celrep.2018.10.074

Ejemplares similares