PKCε Inhibits Neuronal Dendritic Spine Development through Dual Phosphorylation of Ephexin5

Protein kinase C (PKC)-dependent mechanisms promote synaptic function in the mature brain. However, the roles of PKC signaling during synapse development remain largely unknown. Investigating each brain-enriched PKC isoform in early neuronal development, we show that PKCε acutely and specifically re...

Descripción completa

Detalles Bibliográficos
Autores principales: Schaffer, Thomas B., Smith, Jaclyn E., Cook, Emily K., Phan, Thao, Margolis, Seth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371982/
https://www.ncbi.nlm.nih.gov/pubmed/30485813
http://dx.doi.org/10.1016/j.celrep.2018.11.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371982/
https://www.ncbi.nlm.nih.gov/pubmed/30485813
http://dx.doi.org/10.1016/j.celrep.2018.11.005

Ejemplares similares