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PKCε Inhibits Neuronal Dendritic Spine Development through Dual Phosphorylation of Ephexin5
Protein kinase C (PKC)-dependent mechanisms promote synaptic function in the mature brain. However, the roles of PKC signaling during synapse development remain largely unknown. Investigating each brain-enriched PKC isoform in early neuronal development, we show that PKCε acutely and specifically re...
Autores principales: | Schaffer, Thomas B., Smith, Jaclyn E., Cook, Emily K., Phan, Thao, Margolis, Seth S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371982/ https://www.ncbi.nlm.nih.gov/pubmed/30485813 http://dx.doi.org/10.1016/j.celrep.2018.11.005 |
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