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Loss of IGF1R in Human Astrocytes Alters Complex I Activity and Support for Neurons
The insulin/insulin-like growth factor 1 (IGF1) signaling pathways are implicated in longevity and in progression of Alzheimer’s disease. Previously, we showed that insulin-like growth factor 1 receptor (IGF1R) and downstream signaling transcripts are reduced in astrocytes in human brain with progre...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372003/ https://www.ncbi.nlm.nih.gov/pubmed/30056117 http://dx.doi.org/10.1016/j.neuroscience.2018.07.029 |