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Gestational Vitamin D Supplementation Leads to Reduced Perinatal RXRA DNA Methylation: Results From the MAVIDOS Trial

We have previously demonstrated inverse associations between maternal 25(OH)‐vitamin D status and perinatal DNA methylation at the retinoid‐X‐receptor‐alpha (RXRA) locus and between RXRA methylation and offspring bone mass. In this study, we used an existing randomized trial to test the hypothesis t...

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Detalles Bibliográficos
Autores principales: Curtis, Elizabeth M, Krstic, Nevena, Cook, Eloïse, D'Angelo, Stefania, Crozier, Sarah R, Moon, Rebecca J, Murray, Robert, Garratt, Emma, Costello, Paula, Cleal, Jane, Ashley, Brogan, Bishop, Nicholas J, Kennedy, Stephen, Papageorghiou, Aris T, Schoenmakers, Inez, Fraser, Robert, Gandhi, Saurabh V, Prentice, Ann, Javaid, M Kassim, Inskip, Hazel M, Godfrey, Keith M, Bell, Christopher G, Lillycrop, Karen A, Cooper, Cyrus, Harvey, Nicholas C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372078/
https://www.ncbi.nlm.nih.gov/pubmed/30321476
http://dx.doi.org/10.1002/jbmr.3603