CAST/ELKS Proteins Control Voltage-Gated Ca(2+) Channel Density and Synaptic Release Probability at a Mammalian Central Synapse

In the presynaptic terminal, the magnitude and location of Ca(2+) entry through voltage-gated Ca(2+) channels (VGCCs) regulate the efficacy of neurotransmitter release. However, how presynaptic active zone proteins control mammalian VGCC levels and organization is unclear. To address this, we delete...

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Detalles Bibliográficos
Autores principales: Dong, Wei, Radulovic, Tamara, Goral, R. Oliver, Thomas, Connon, Montesinos, Monica Suarez, Guerrero-Given, Debbie, Hagiwara, Akari, Putzke, Travis, Hida, Yamato, Abe, Manabu, Sakimura, Kenji, Kamasawa, Naomi, Ohtsuka, Toshihisa, Young, Samuel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372087/
https://www.ncbi.nlm.nih.gov/pubmed/29996090
http://dx.doi.org/10.1016/j.celrep.2018.06.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372087/
https://www.ncbi.nlm.nih.gov/pubmed/29996090
http://dx.doi.org/10.1016/j.celrep.2018.06.024

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