CAST/ELKS Proteins Control Voltage-Gated Ca(2+) Channel Density and Synaptic Release Probability at a Mammalian Central Synapse

In the presynaptic terminal, the magnitude and location of Ca(2+) entry through voltage-gated Ca(2+) channels (VGCCs) regulate the efficacy of neurotransmitter release. However, how presynaptic active zone proteins control mammalian VGCC levels and organization is unclear. To address this, we delete...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Wei, Radulovic, Tamara, Goral, R. Oliver, Thomas, Connon, Montesinos, Monica Suarez, Guerrero-Given, Debbie, Hagiwara, Akari, Putzke, Travis, Hida, Yamato, Abe, Manabu, Sakimura, Kenji, Kamasawa, Naomi, Ohtsuka, Toshihisa, Young, Samuel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372087/
https://www.ncbi.nlm.nih.gov/pubmed/29996090
http://dx.doi.org/10.1016/j.celrep.2018.06.024

Ejemplares similares

Ejemplares similares