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Development of a fluorescence-based cellular apoptosis reporter

Evasion of apoptosis is a hallmark of human cancer, and a desired endpoint of many anticancer agents is the induction of cell death. With the heterogeneity of cancer becoming increasingly apparent, to understand drug mechanisms of action and identify combination therapies in cell populations, the de...

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Detalles Bibliográficos
Autores principales: Balderstone, Lucy A, Dawson, John C, Welman, Arkadiusz, Serrels, Alan, Wedge, Stephen R, Brunton, Valerie G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOP Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372133/
https://www.ncbi.nlm.nih.gov/pubmed/30353887
http://dx.doi.org/10.1088/2050-6120/aae6f8