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O-GlcNAcylation of PERIOD regulates its interaction with CLOCK and timing of circadian transcriptional repression

Circadian clocks coordinate time-of-day-specific metabolic and physiological processes to maximize organismal performance and fitness. In addition to light and temperature, which are regarded as strong zeitgebers for circadian clock entrainment, metabolic input has now emerged as an important signal...

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Detalles Bibliográficos
Autores principales: Li, Ying H., Liu, Xianhui, Vanselow, Jens T., Zheng, Haiyan, Schlosser, Andreas, Chiu, Joanna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372208/
https://www.ncbi.nlm.nih.gov/pubmed/30703153
http://dx.doi.org/10.1371/journal.pgen.1007953