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A Notch-mediated, temporal asymmetry in BMP pathway activation promotes photoreceptor subtype diversification

Neural progenitors produce neurons whose identities can vary as a function of the time that specification occurs. Here, we describe the heterochronic specification of two photoreceptor (PhR) subtypes in the zebrafish pineal gland. We find that accelerating PhR specification by impairing Notch signal...

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Detalles Bibliográficos
Autores principales: Cau, Elise, Ronsin, Brice, Bessière, Laurianne, Blader, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372210/
https://www.ncbi.nlm.nih.gov/pubmed/30703098
http://dx.doi.org/10.1371/journal.pbio.2006250