Pathogen diversity drives the evolution of generalist MHC-II alleles in human populations

Central players of the adaptive immune system are the groups of proteins encoded in the major histocompatibility complex (MHC), which shape the immune response against pathogens and tolerance to self-peptides. The corresponding genomic region is of particular interest, as it harbors more disease ass...

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Detalles Bibliográficos
Autores principales: Manczinger, Máté, Boross, Gábor, Kemény, Lajos, Müller, Viktor, Lenz, Tobias L., Papp, Balázs, Pál, Csaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372212/
https://www.ncbi.nlm.nih.gov/pubmed/30703088
http://dx.doi.org/10.1371/journal.pbio.3000131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372212/
https://www.ncbi.nlm.nih.gov/pubmed/30703088
http://dx.doi.org/10.1371/journal.pbio.3000131

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